Evaluating Lung Cancer with Tumor Markers: CEA, CA 19-9 and CA 125

Aim: Lung cancer (LC) is a common and mortal malignancy. Tumor biomarkers are measurable biochemicals associated with cells. markers cannot diagnose cancer; instead, they can be used as laboratory tests to support the diagnosis. In this study, we aimed investigate place of tumor in lung histological types. Materials Methods: The study included 121 stage IV patients, 79% whom were male, between ages 33-84, who admitted chest diseases thoracic surgery departments our hospital. CEA, CA 19-9, 125 studied immunoassay technique. Its effects on survival investigated. LDH was analyzed for determination burden transformation by enzymatic method. Patients divided into groups according number metastases after diagnosis evaluate clinical parameters detail. Result: CEA adenocarcinoma type, 19-9 small cell subtype, squamous type significantly higher than other subtypes (p = 0.037, p 0.031, 0.021). values increased patients more two (p=0.047, p=0.039, p=0.028). When three <3cm, 3-5cm, >5cm, levels proportion diameter, while 12-5 did not show statistical relationship. Conclusion: help predict patients' prognosis.